Pavillon Jean-Coutu, Room 2143
Telephone: 514-343-6440 or 343-6111 #3342
Fax: 514-343-2102
Email: pierre.moreau@umontreal.ca

Teaching Domains

• Pharmacology

• Physiology

Research Themes

• Vascular calcification, vascular stiffness and isolated systolic hypertension

• Diabètes and vascular stiffness

• Hypertension-induced vascular remodeling

Current Research Projects

• Mechanisms responsible for the regression of vascular calcification

• Study of cell-matrix interactions in the control of vascular stiffness

• Role of glycation end-products in diabètes-induced vascular calcification

• Impact of diabètes and metabolic syndrome in protein carboxylation

Selected Publications

Beaucage P, Iglarz M, Servant M, Touyz RM, Moreau P. Position of Src family tyrosine kinases in the interaction between the renin angiotensin and the endothelin systems in vivo. J Hypertens 2005;23:329-335.

Dao HH, Essalihi R, Bouvet C, Moreau P. Evolution and modulation of vascular aging: focus on medial calcification (elastocalcinosis) of large arteries. Cardiovasc Res 2005;66:307-317.

Bouvet C, Gilbert, LA, Girardot, D, deBlois D, Moreau P. Different involvement of extracellular matrix components in small and large arteries during chronic NOS inhibitior. Hypertension 2005;45:432-437.

Essalihi R, Dao HH, Gilbert LA, Bouvet C, McKee MD, Moreau P. Regression of Medial Elastocalcinosis in the Rat Aorta: A New Vascular Function for Carbonic Anhydrase. Circulation 2005;112:1628-1635.

Dao HH, Bouvet C, Beaucage P, Larivière R, Servant M, de Champlain J, Moreau P. Endothelin is both a trophic factor and a mitogen in small arteries in vivo. Cradiovasc Res 2006;71:61-68. Editorial by M. Takahashi, p. 4-5.

Bouvet C, Peeters W, Moreau S, deBlois D, Moreau P. A new rat model of diabetic macrovascular complication. Cardiovascular Research 2007;73:504-511. Editorial by A. Nitenberg, p. 450-451.

Essalihi R, Zandvliet M, Moreau S, Gilbert LA, Bouvet C, Lenoël C, Nekka F, McKee MD, Moreau P. Distincts effects of amlodipine treatment on vascular elastocalcinosis and stiffness in a rat model of isolated systolic hypertension. J Hypertens 2007;25:1879-1886.

Bouvet C, Moreau S, Blanchette J, deBlois D, Moreau P. Sequential activation of MMP-9 and TGF-ß in arterial elastocalcinosis. Atheroscler Thromb Vasc Biol 2008;28:856-861.

 

Last update:  2011-06-07